Sotiriou et al report in this issue

Sotiriou et al. (2016) report in this issue of Molecular Cell that RAD52 is required for the BIR-mediated repair of collapsed DNA replication forks in response to oncogene-induced replication stress. Their data are fully consistent with ours.
Experimental Procedures
Author Contributions
Acknowledgments We thank Dr. Claudia Lukas, Dr. Jiri Lukas, and members of the I.D.H. laboratory for useful discussions and Hocine Mankouri and Ying Liu for critical reading of the manuscript. We also thank Thanos Halazonetis for sharing data prior to submission. Work in the authors’ laboratory is funded by the Danish National Research Foundation (DNRF115), The European Research Council (ERC Project Number 321717), and The Nordea Foundation. R.B. and S.M. were recipients of Danish Medical Research Council fellowships (DFF-4004-00155B, DFF-6110-00169B, and DFF-6110-00243B).
Introduction In order to reduce the enormous utilization of fossil fuels and other related environmental issues existing in our day-to-day life activities, scientific C527 has been taking efforts to develop eco-friendly energy storage devices with high energy and power density ratings, ultra-fast charge/discharge capacity, long cycle life and lower maintenance costs [1], [2], [3], [4]. Among the presently available energy storage devices, supercapacitors have acquired a tremendous interest, because of their remarkable characteristics such as higher power density than batteries and higher energy density than traditional capacitors in their device performance [5], [6], [7], [8], [9]. These advantages are essential for their real time applications in all portable electronic devices, electric vehicles, instant switches, back-up power supply, motor starter, industrial power and energy management, etc. [10]. Based on the energy storage mechanism, supercapacitor electrode materials may be classified into two types: (i) Pseudocapacitors and (ii) Electrochemical double layer capacitors (EDLC\'s). Pseudocapacitor electrodes employ redox reaction mechanism for charge storage and are generally based on metal oxides and conducting polymers, whereas, electrochemical double layer capacitors store charges through an accumulation of electrostatic charges at the electrode/electrolyte interface and involve typically carbonaceous materials having appreciably high specific surface area [11], [12], [13]. Due to the multiple oxidation states of pseudocapacitor electrode materials, they tend to deliver higher specific capacitance and energy density values than that of EDLC electrode materials [14]. It is well known that, nanostructured transition metal oxides are the most promising candidates as electrode for pseudocapacitors due to their attractive properties such as environmentally friendly, high theoretical capacitance, low cost and easily abundant [15], [16]. Numerous investigations have been made so far on transition metal oxides such as MnO2 [17], Co3O4 [18], NiO [19], V2O5 [20], ZnO [21], TiO2 [22] and MoO3 [23] in order to utilize them as pseudocapacitor electrodes in recent years. Nevertheless, transition metal oxides are having few limitations such as poor electrical conductivity, poor electrochemical stability and lower ion diffusion rates, which restrict their practical applications [24]. On the other hand, binary metal oxides such as NiCo2O4 [25], ZnCo2O4 [26], NiMoO4 [27], MnMoO4 [28], CoMoO4 [29] and SnMoO4 [30] have been employed as alternative electrode materials in order to address the aforementioned issues, owing to the multiple oxidation states for redox reactions and thus, leading to an increase in the specific capacitance as well as electrical conductivity.