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Because SAPK mediates hyperosmolar stress induced Hand and H
2018-10-31
Because SAPK mediates hyperosmolar stress-induced Hand1 and Hand1-dependent PL1 (Awonuga et al., 2011), we tested whether stress-induced lineage choice during hypoxia was SAPK-dependent. Since hyperosmolar stress induces the first lineage but not later lineages from TSC (Liu et al., 2009), and SAPK
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igf 1 antagonist The present results found that
2018-10-31
The present results found that under osteogenic induction, hydrostatic pressure promoted the igf 1 antagonist of marker genes for early osteogenic differentiation in BMSCs through the activation of RhoA/ROCK. It was reported that the activated RhoA/ROCK proteins enhanced myosin motor activity throu
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With these results we provide evidence that the transplantat
2018-10-31
With these results, we provide evidence that the transplantation of iPSC-derived NSCs could have a beneficial role in modifying the course of SMARD1. Regarding the translational safety of iPSC-derived cells, one major finding of this study is that adverse events such as tumorigenesis or abnormal gro
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Based on our findings and
2018-10-31
Based on our findings and the recent literature, we propose the following model of sebocyte differentiation (Figure 7). First, subsets of LGR6- and LRIG1-expressing calcium ionophore residing in the upper HF and periphery of the SG constitute the bona fide stem cells of the sebocyte lineage (Page e
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Constitutive expression of Puro TK
2018-10-31
Constitutive expression of Puro/TK from the ubiquitously active mPGK promoter might hinder therapeutic applications of this approach. Indeed, these highly immunogenic prokaryotic/viral proteins can be presented on the cell surface of the gene-corrected EHT 1864 by the major histocompatibility comple
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To confirm this we transplanted
2018-10-31
To confirm this, we transplanted mutant order ACA into wild-type hosts in a reverse transplant setting. Either 5 × 105 OsxCre;iDTR mutant or control bone marrow cells, competed with 5 × 105 SJL bone marrow cells in a 1:1 ratio, were transplanted into lethally irradiated SJL hosts. When cells from O
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br The connection between the yield
2018-10-30
The connection between the yield point of a material and the surface tension caspase pathway of its particles As follows from Fig. 1, the surface tension coefficient rapidly decreases with a decrease in the particle size R/δ of the material, for particles with sizes less than 20δ (about 20nm). I
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The morphological features of the MnO modified materials
2018-10-30
The morphological features of the MnO2-modified materials obtained are clearly visible in Figs. 2 and 3 which show the surfaces of these materials, imaged by SEM at different magnifications. It can be seen that high-silica samples (see Fig. 2a) have a monolithic structure, apparently consisting of c
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Literacy is a fundamental resource highly
2018-10-30
Literacy is a fundamental resource highly correlated with educational attainment. Broadly, literacy has been defined as using printed and written information to function in society, to achieve one’s goals, and to develop one’s knowledge and potential. Literacy enables individuals to gain knowledge a
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Hone et al Hone Jarden Schofield
2018-10-30
Hone et al. (Hone, Jarden, Schofield, & Duncan, 2014) contend that policy-makers are increasingly interested in assessments of health that include measures of positive mental health and well-being, with an emphasis on strengths-based approaches as opposed to an illness-focus. Positive mental health
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Increasing attention is therefore being
2018-10-30
Increasing attention is therefore being paid to intervention-context interactions, and their influence on implementation processes and hypothesized outcomes (Moore et al., 2014). It is important to understand how practitioners engage with interventions because this can provide insights into why fide
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This study could be an important tool in
2018-10-30
This study could be an important tool in FRMS [20] implementation, with its multi-layered defensive strategies to manage fatigue, enhancing the importance of crew monitoring in facilitating a higher control in the observed variables. Sleep hygiene techniques/education and fatigue countermeasures are
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We report a new electrochemical biosensor
2018-10-30
We report a new electrochemical biosensor for CRP detection as part of a first step in the development of simple, multi-electrode microfluidic clinical diagnostic tools. One of the biggest challenges with multi-analyte electrochemical biosensors is localization of the affinity agents on individual e
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Esos sucesos convierten a la
2018-10-30
Esos sucesos convierten a la crisis económica internacional iniciada en 2008 en una crisis política mundial de muy amplio alcance y variadas manifestaciones, que cuestiona las bases del orden neoliberal existente. Pero la persistencia y resistencia de este orden a desaparecer, ha desencadenado o amp
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El seguimiento de la versi n pbc
2018-10-30
El seguimiento de la versión pbc de disminución del gasto, seguramente entrañará, CCT251545 analogue escala rural, una revisión de los programas no tan rigurosa como debiera, pero pondrá sobre la mesa de análisis dos de los puntos más importantes del desarrollo rural y la política pública: Estos do
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