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br Discussion Over the past two decades the
2019-04-22
Discussion Over the past two decades, the incidence of second primary malignancy has progressively risen among cancer survivors and is an issue of increasingly greater concern in oncology. The increasing incidence may be due to the elevated rate of early cancer detection, improved cancer treatmen
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wst-1 assay The animal model described here is also expected
2019-04-22
The animal model described here is also expected to lead us to design mechanism-based therapeutic interventions for bone metastases of NB. In this context, it is notable that the selective COX-2 inhibitor NS-398, which is known to selectively inhibit COX-2 without affecting COX-1 activity [30], inhi
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br Case report Radiographs showed a
2019-04-22
Case report Radiographs showed a lytic lesion in the left ilium adjacent to the sacroiliac joint (Fig. 1). Computed tomography (CT) (Fig. 2) showed a 5.5×5.0×3.4cm3 lytic lesion in the left ilium; the sacrum was not involved. The lesion was of uniform density with no bone or cartilage matrix form
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br Introduction Bone marrow adipocytes are one of the most
2019-04-22
Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog
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Most forms of AVNRT are created by reentry between two
2019-04-22
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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No es xito peque o
2019-04-22
No es éxito pequeño que “bajo la dirección del maestro Stols” (así indica el colofón del libro) se lograse tal parecido con ellas, pero conviene subrayar que Jusep Torres Campalans no es mera mímesis material de la colección Le goût de notre temps sino también, o ante todo, estructural. El Picasso d
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GW788388 br Martyn Plummer and colleagues September analyse
2019-04-22
Martyn Plummer and colleagues (September, 2016) analyse the global burden of cancers attributable to infections in 2012. Despite the relatively low attributable proportion compared with other infectious agents, liver flukes, including and , were estimated to have caused 1300 new cases of cholangi
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The present study determined the effect of DCA on
2019-04-22
The present study determined the effect of DCA on VSMC calcification in vitro and in atherosclerotic ApoE-/- mice in vivo. We found that SB525334 non-toxic concentrations of DCA, did not affect VSMC viability, induced calcification of VSMC in culture and increased atherosclerotic vascular calcifica
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br The Medical Education Partnership Initiative MEPI is an i
2019-04-20
The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that ampa
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Outra implica o envolvida com as os
2019-04-20
Outra implicação envolvida com as os e que tem sido uma das principais bandeiras levantada por entidades contrárias é OG-L002 cost considerada terceirização da saúde pública. A terceirização foi assumida por alguns agentes envolvidos no processo, como o ex-secretário de saúde paulista e sanitarista
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The authors of the NCCN non
2019-04-20
The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w
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ccr2 inhibitor Causative genes for ARVC and their
2019-04-20
Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table
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Any abnormality causing a loss of function in the
2019-04-20
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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O Contrato de Gest o na percep o de Pahim
2019-04-20
O Contrato de Gestão, na percepção de Pahim, constitui um instrumento importante como mecanismo que explicita necessidades específicas de serviços por parte daquele que deve planejar Y-27632 oferta de assistência à saúde, no caso a secretaria estadual ou mesmo municipal. Mas a autora ressalta que, d
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Agosto toma la medida del relato hist rico
2019-04-20
Agosto toma la medida del relato histórico en algunas ocasiones, de la crónica periodística en otras, para obtener una narración que ha llegado a entremezclarse con la realidad, o al menos con una investigación académica bien documentada, al grado tal que es bastante común encontrarla citada en artí
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