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Findings conflict regarding the influence of ARIs on apoptos
2018-11-14
Findings conflict regarding the influence of 5ARIs on apoptosis. Bass et al. (2009) showed no effect on caspase 3 in a randomized, placebo-controlled, presurgical 30-day finasteride intervention in localized prostate cancer (N=22 in each arm). However, results of two dutasteride studies, both using
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On the basis of our genetic findings that
2018-11-14
On the basis of our genetic findings that hexokinase 2 (HK2)-mediated aerobic glycolysis, known as the Warburg effect, drives prostate tumor growth in xenograft model bearing /p53-deficient murine or human prostate cancer myeloperoxidase (Wang et al., 2014), we designed preclinical studies to deter
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The combination of romidepsin and bryostatin
2018-11-14
The combination of romidepsin and bryostatin-1 has been shown to be one of the best inducers of latent HIV-1 in primary CD4+ T LY335979 (Laird et al., 2015). However, bryostatin-1 has been showed to be involved in the modulation of NFkB and NFAT (Williams et al., 2004) and romidepsin is known to af
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ABA overall drug retention time was similar across all
2018-11-14
ABA overall drug retention time was similar across all groups (p=0·11). However, as could be expected, ABA drug retention until discontinuation for ineffectiveness was much shorter among ‘inadequate responders’ (median time in years: GR, 4·7, RR: 5·3, IR: 2·0, p=0·03). The proportion of patients wit
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Although the serum levels of some inflammatory cytokines suc
2018-11-14
Although the serum levels of some inflammatory cytokines such as TNF-α were not elevated in H. pylori-infected HFD mice, the increased abundance of Desulfovibrionaceae which can produce endotoxins and the compromised intestinal barrier s ibuprofen some doubt on the role of inflammation. In addition
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In this issue of EBioMedicine Enroth and colleagues present
2018-11-14
In this issue of EBioMedicine, Enroth and colleagues () present a comprehensive study that analyzes the individual contribution of factors related to the collection and long-term sample storage in a highly homogenous group of Northern European subjects (). Taking advantage of the sampling strategy o
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Sialylated IgG has been reported to
2018-11-14
Sialylated IgG has been reported to have anti-inflammatory properties likely mediated through interaction with the murine C-type lectin receptor SIGN-R1 (a homologue of the human DC-SIGN) and FcyRIIb (Kaneko et al., 2006; Collin and Ehlers, 2013). In our study, we found that total IgG preserved an a
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br Experimental design materials and
2018-11-14
Experimental design, materials and methods Acknowledgements The authors thank Regione Lombardia (CoVAL project, no.1723) for the financial support to the research activities. Data The FTIR of the fresh MPAB at wave numbers from 400 to 4000cm−1 are given in Fig. 1. The SEM image of prepared
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Samples were biofunctionalized using plasma
2018-11-14
Samples were biofunctionalized using plasma electrolytic oxidation on a custom-made laboratory setup. Details regarding the experimental setup can be found in [1]. Plasma electrolytic oxidation is an electrochemical process, which drives uniform growth of the titanium oxide (TiO2) layer on the surfa
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br Data CMP experiments were performed on the titanium plate
2018-11-14
Data CMP experiments were performed on the titanium plates by altering the sample surface through various CMP conditions [1]. First, slurry particle size and stability were evaluated through particle light scattering based particle size measurement by using Coulter LS 13 320 equipment as can be s
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A-1210477 What is more contrary to hypothesis mean activity
2018-11-14
What is more, contrary to hypothesis (5), mean activity was also negatively correlated with trait anxiety in the superior PFC (Fig. 4, bottom right). So, trait anxiety was negatively correlated with prefrontal and positively with visual cortical activity. Consistently, in adolescents suffering from
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These sections will be broadly divided into implicit and
2018-11-14
These sections will be broadly divided into implicit and explicit processes, as the paradigms used to investigate these are quite different. However, it NVP-TNKS656 is noted that this distinction may be too simplistic and that the boundaries between implicit and explicit emotion regulation are likel
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Our findings indicate that memory cueing can modulate positi
2018-11-14
Our findings indicate that memory cueing can modulate positive interpretations of new ambiguous scenes, while it did not impact negative interpretations. In line with previous studies, the absence of an effect of cueing on negative interpretations coincided with a general tendency of these participa
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Our results suggest that interindividual differences in neur
2018-11-13
Our results suggest that interindividual differences in neural mirroring are related to successful cooperation. Yet, the causal direction underlying this relation remains an open question. Better interpersonal coordination likely is the result of higher general levels of neural mirroring. Previous r
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Entre sus diversas novelas quiz sea en Demian
2018-11-13
Entre sus diversas novelas, quizá sea en Demian donde queda más clara esta presencia andrógina en el universo hessiano (y que se decanta por el adolescente como su portador temporal). La historia cuenta la vida de Emil Sinclair y su relación con Demian y su sibilina madre, así como con una figura fe
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