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br Simulation results and discussion
2018-10-29
Simulation results and discussion Conclusions This study used the intelligent software called DesignBuilder, which employs the powerful and comprehensive cyclosporin simulation engine EnergyPlus, to simulate indoor thermal comfort and energy issues. Three scenarios of the indoor environment we
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br Case Report A day old male child weighing
2018-10-29
Case Report A 5-day-old male child, weighing 2.5 kg, was admitted in the emergency department with complaints of an inability to pass meconium, severe abdominal distension, and bilious vomiting. The child had passed meconium once within 24 hours of life. On examination, the heart rate was 140 bea
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The treatment of an incidental
2018-10-29
The treatment of an incidental aneurysm accompanying a TAPI-1 tumor slightly differs from that of an incidental aneurysm. Owing to the presence of an aneurysm, complete removal of the tumor poses a high intraoperative risk, and the long-term risk of aneurysm rupture was estimated to be 10–38%. Thus,
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Nanaomycin A However free radicals have also been suggested
2018-10-29
However, free radicals have also been suggested to cause DM [11]. Although free radicals typically originate from the surrounding environment, several physiological and biochemical processes in the human body also produce reactive oxygen species, such as the superoxide radical, hydroxyl radicals, an
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It is intriguing to note that high
2018-10-29
It is intriguing to note that high cholesterol feeding improved antioxidants (when compared to controls) in a few instances. Such improvements in antioxidants are an adaptive mechanism by the organism and have been reported in the literature [43]. Although there was no synergy among the dietary fenu
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Unfortunately existing cytogenetic karyotyping methods are l
2018-10-29
Unfortunately, existing cytogenetic karyotyping methods are labor intensive, requiring at least 15 fixed metaphase preparations, subsequent DAPI staining, and analysis with an epi-fluorescence microscope equipped with specialized digital imaging software. Conventional karyotyping is expensive (∼$400
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br Results br Discussion We first identified surface markers
2018-10-29
Results Discussion We first identified surface markers that distinguish the earliest prechondrocytes from nonchondrogenic RGDfK cost types; subsequent comparison of prechondrocytes with differentiated, definitive resting (immature) chondrocytes located in the superficial periarticular regions
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For some genes the difference in transgene expression
2018-10-26
For some genes, the difference in transgene expression in BM/blood and other target organs can be both quantitative and qualitative. For example, the activities of introduced TAK-875 α-glucosidase, which is deficient in a lysosomal glycogen storage disorder, Pompe disease, were different in blood,
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The following are the supplementary data related to this
2018-10-26
The following are the supplementary data related to this article. Conflict-of-interest disclosure Acknowledgments The authors would like to thank Ms. Kathleen Makielski for proofreading the manuscript. This work was supported by National Natural Science Foundation of China (grant number 81372
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It is the first time to
2018-10-26
It is the first time to report the involvement of miRNA-30c in enhancing sphere formation and neural differentiation. The relationships of miRNA-30c and osteodifferentiation and adipocyte differentiation have been discussed previously (Gao et al., 2011; Karbiener et al., 2011; Vimalraj and Selvamuru
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We previously discovered that ATM in addition to serving man
2018-10-26
We previously discovered that ATM, in addition to serving many roles in cell-cycle regulation and DNA damage response, also functions as a key epigenetic regulator in neurons, likely underlying the ataxic symptoms as well as neurodegeneration. ATM indirectly regulates nuclear-cytoplasmic shuttling o
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Previously it was demonstrated that induced NP iNPs can be
2018-10-26
Previously, it was demonstrated that induced NP (iNPs) can be directly converted from mouse somatic vitamin d receptor by overexpressing various TF combinations (Han et al., 2012; Kim et al., 2011; Lujan et al., 2012). Kim et al. (2011) first demonstrated that expandable iNPs could be generated from
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Introduction of the lentiviral vector LV platform has spurre
2018-10-26
Introduction of the lentiviral vector (LV) platform has spurred applications of gene therapy based on the transplantation of ex-vivo-engineered, autologous hematopoietic stem and progenitor cells (HSPCs) (Naldini, 2015). Recent clinical trials for patients affected by primary immunodeficiencies, hem
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Though some microscale pedestrian features such as
2018-10-26
Though some microscale pedestrian features, such as esthetics, were consistently better in high-income/White neighborhoods, a pattern emerged showing that hcv protease inhibitors certain microscale pedestrian features were better in low-income or high-minority residential neighborhoods. In resident
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Our findings also suggest that increase in contribution
2018-10-26
Our findings also suggest that increase in contribution of income to inequalities could be related to changes in the distribution of income within Canada and the United States. Recent work by Bernabé and Marcenes (2011) suggest the degree of state income inequality may be attributed to inequalities
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