• The Fontan circulation When first

  2019-07-01

  

  The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital bosentan structure disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, which creates a t

• South Africa was the first African

  2019-07-01

  

  South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age

• br Genetic basis Similar to

  2019-07-01

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• In contrast the prevalence of BS or Brugada type

  2019-07-01

  

  In contrast, the prevalence of BS or Brugada-type ECG in Asian countries is relatively high. Type 1 ECG has been identified in 0.17% of 3907 asymptomatic Filipinos [24] and in 0.13% of 20,652 Taiwanese patients who visited the hospital for non-cardiovascular reasons [25]. Brugada-type ECG has been

• br Methods We described our strategies for ablating AF

  2019-07-01

  

  Methods We described our strategies for ablating AF in previous reports [34–36]. Therefore, we will discuss our methods for CFAE ablation, including CFAE-ablation combined with PVI, below. Results Representative cases of CFAE-ablation Conclusions Acknowledgments Characteristics of

• br Material and methods br Results

  2019-07-01

  

  Material and methods Results Discussion In our series, fracture progression was noted in 53% of the lesions and 5 patients presented with new fractures after RT. Previous studies reported on the rate of pathologic fractures after single or multifraction RT; however, they did not stratify be

• The requirements for establishing this

  2019-07-01

  

  The requirements for establishing this arrhythmia are as follows: (1) a slow pathway (or maybe a fast pathway) should not have retrograde conduction; and (2) the refractory Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) of of the distal common pathway must be shorter than the difference in t

• br Conclusion br Funding br Conflict of interest br

  2019-07-01

  

  Conclusion Funding Conflict of interest Acknowledgments Introduction Ventricular tachyarrhythmias (VTs) are life-threatening events that result in hemodynamic compromise; therefore, patients often require immediate treatment such as electrical cardioversion. Despite appropriate manage

• Lo and colleagues also add to the evidence that

  2019-07-01

  

  Lo and colleagues also add to the evidence that MDA might need to be widened beyond school-aged children (5–14 years). Different frequencies of treatment are known to be needed for communities with different intensities of infection, but less appreciated is that different age groups need to be treat

• A partir de las consideraciones que distinguen la

  2019-07-01

  

  A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado TAK-242 molecular tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun con la pr

• br Since the publication of Stillbirths Series in attention

  2019-06-29

  

  Since the publication of Stillbirths Series in 2011, attention to the more than 2·6 million stillbirths that occur every year has become more visible in global and national maternal and neonatal health strategies. However, we continue to neglect the millions of women who experience not only still

• U-104 of Stimulated IUI is much more effective than

  2019-06-29

  

  Stimulated IUI is much more effective than natural U-104 of or controlled ovarian hyperstimulation treatment. In four randomized trials of patients with unexplained subfertility, pregnancy rates were higher when IUI was performed in stimulated cycles than in natural cycles [odds ratio (OR): 2.14; 9

• A structured inherited arrhythmia or heart disease clinic pr

  2019-06-29

  

  A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli

• Introduction Despite advances in breast cancer treatment bon

  2019-06-29

  

  Introduction Despite advances in breast cancer treatment, bone remains the most common site of Fmoc-Phe-OPfp of [1,2] occurring in around 70% of patients with metastatic disease [3]. Bone metastases are incurable and associated with significant morbidity in terms of fractures, pain, and reduced qu

• The principal difference between BrS and ERS is

  2019-06-29

  

  The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p

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