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Flow cytometric immunophenotyping showed the circulating bla
2019-05-23
Flow cytometric immunophenotyping showed the circulating blasts expressed CD19, CD20, CD22, CD24 partial, HLA -DR, CD34, and TdT. There was variable expression of the myeloid markers CD15 and CD33. The blasts were negative for CD3, CD10, MPO, and all other T-cell, myeloid, and monocytic markers eval
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The patient was consented to treatment on clinical trial
2019-05-23
The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p
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The very fact that providing a greater number of
2019-05-22
The very fact that providing a greater number of doses of IPTp-SP is incrementally effective, even in settings where the parasite is sensitive, also highlights the potential benefit of interventions using more effective drugs. This finding means there is either scope to improve clearance of existing
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We used MRI images taken to weeks after a crisis
2019-05-22
We used MRI images taken 1 to 8 weeks after a crisis to explore basal ganglion involvement and found restricted sodium channel blockers at the basal ganglion. This finding suggests that cytotoxic damage to the basal ganglion persists post-crisis. When MRI images were obtained much longer after crisi
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Regarding the expression of NKp NCR
2019-05-22
Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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To overcome these resistance mechanisms in APL cells a numbe
2019-05-22
To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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In DC from A group only
2019-05-22
In DC from A group only few genes appeared to be significantly and highly modulated (10 out of 84). The HIV natural ligands CCL4 and CD4, the HIV induced transcription factor IRF1 as well as the apoptotic genes BAD and CASP8 resulted down-regulated compared to monocytes at all the considered time po
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In the APHRS survey most respondents
2019-05-22
In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigat
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Residing in West Germany also decreased BIS
2019-05-22
Residing in West Germany also decreased BIS persistence. In 2015, Jacob et al. demonstrated in 4,915 BC women that the treatment discontinuation rate is higher in West Germany than in East Germany [1]. Finally, our study returned one outcome that requires careful discussion: we found that private he
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De acuerdo con los planteamientos anteriores pensemos en
2019-05-22
De acuerdo con los planteamientos anteriores pensemos en la propuesta que se obtendría desde la obra de Villoro respecto RGDfK la situación política para un miembro perteneciente a una comunidad indígena, en tanto que además de pertenecer a ella se reconozca como ciudadano del Estado-nación, de esta
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br Discussion The natural history of PMF is characterized
2019-05-21
Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable
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El eje dram tico de En la prisi n
2019-05-21
El eje dramático de En la prisión… se va desarrollando HG-9-91-01 través de los relatos que el Profesor, un militante de la vanguardia política revolucionaria cubana, sueña que, a su vez sueña, que narra a un grupo de “negros” durante un agobiante verano habanero de los años noventa. Todo sucede den
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Table shows the results of achieving ECV for
2019-05-21
Table 3 shows the results of achieving ECV for atrial arrhythmia in this study. There was no significant between-group difference in the number of ECV attempts or the prevalence of successful ECV. The number of days to ECV in OAC-naïve patients was significantly less in the NOACs group (n=72) compar
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De acuerdo con el historiador argentino la independencia de
2019-05-21
De acuerdo con el historiador argentino, la independencia de las colonias españolas en América es el resultado de una degradación del poder español que había comenzado desde 1795. En primera instancia, el poder de la Corona española se hacía cada vez más lejano, pues la pérdida de la guerra de Españ
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AMG-900 Introduction Myelodysplastic Syndrome MDS is a
2019-05-21
Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal
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