• Brugada syndrome BS is a hereditary arrhythmogenic disease c

  2019-04-18

  

  Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada

• br Conclusion br Conflict of

  2019-04-18

  

  Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue

• The aim of this study was to determine the therapeutic

  2019-04-18

  

  The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o

• At the mechanistic level our

  2019-04-18

  

  At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,

• The two statements from the BRICS partnership could help to

  2019-04-18

  

  The two statements from the BRICS partnership could help to inform how best emerging economies can contribute to achievement of ambitious global targets for tuberculosis control. BRICS and other economies in transition have a great responsibility and the potential to contribute to all aspects of car

• Es en virtud de estas afirmaciones que propongo retomar una

  2019-04-18

  

  Es en virtud de estas afirmaciones que propongo retomar una perspectiva literaria para pensar los modos diversos de concebir la representación, así como atender fgfr inhibitor la insistencia con que se acude a “lo real” (e incluso al “realismo”) para caracterizar las crónicas de la conquista en gene

• Pero en los a os

  2019-04-18

  

  Pero en los años noventa, como refere Brito, al inventariarse los resultados de la estrategia de desarrollo y de las reformas adelantadas en la década anterior, es decir ante una revisión “crítica” del “Consenso de Washington”, fue evidente que los costos en términos de inequidad y dualización socia

• br Conflict of interest br Introduction Patients with struct

  2019-04-17

  

  Conflict of interest Introduction Patients with structural heart disease have an increased risk of sudden cardiac death, secondary to ventricular tachyarrhythmias in most cases. Implantable cardioverter–defibrillators (ICDs) are the treatment of choice. However, ventricular tachyarrhythmias ca

• According to the labeling of dabigatran

  2019-04-17

  

  According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage

• 5 aminolevulinic acid br La poes a temprana de Carlos Pellic

  2019-04-17

  

  La poesía temprana de Carlos Pellicer (1899–1977) ejemplifica un cambio fundamental en la lírica hispanoamericana. Su obra revela la transición entre el cosmopolitismo ahistórico y exotista y una nueva poesía de conciencia histórica que no solo retoma la historia y la realidad propias de Hispanoam

• thapsigargin El impulso universalista de Sur afect de distin

  2019-04-17

  

  El impulso universalista de Sur afectó de distintas formas su política editorial. En general transitó los marcos de los ideales de Victoria Ocampo, quien además de directora era mecenas del proyecto, y los de José Bianco, que desempeñó por más de 20 años las labores de la secretaría de redacción. La

• In our study acute toxicities were mild

  2019-04-17

  

  In our study, acute toxicities were mild, and there were no Grade 3 or above hematologic toxicities. Only one patient (3.2%) had Grade 3 esophagus toxicity and three patients (9.7%) had Grade 3 lung toxicity. Compared with studies that investigated regimens of oxaliplatin and 5-FU/leucovorin, the pr

• In summary we present a rare case

  2019-04-17

  

  In summary, we present a rare case of magnesium sulfate-induced fetal bradyarrhythmia caused by prolongation of the refractory period of the atrioventricular node in the case of blocked premature atrial contractions. Clinicians should consider fetal bradyarrhythmia when the baseline fetal heart rate

• At baseline the patient exhibited normal A

  2019-04-17

  

  At baseline, the patient exhibited normal A–H (57ms) and H–V (44ms) intervals, with a sinus ion channel length of 784ms. Both antegrade and retrograde dual atrioventricular (AV) nodal physiologies were assessed by atrial and ventricular extrastimulus (Fig. 2), without inducible AV nodal reentrant t

• ddhCTP br Results br Discussion We

  2019-04-17

  

  Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat

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